Speaker: Stephen Peiper, MD

Topic:

"Strategies to Prevent Metastases: Blockade of Migration and KiSS them Goodbye? "

When:

Monday, October 30, 2006
12:00PM – 1:00PM
 

Location:

Baldwin Auditorium
Robert H. Lurie Medical Research Center
303 East Superior Street, 1st floor

Tomita K, Niida A, Oishi S, Ohno H, Cluzeau J, Navenot JM, Wang ZX, Peiper SC, Fujii N. Structure-activity relationship study on small peptidic GPR54 agonists. Bioorg Med Chem. 2006 Nov 15;14(22):7595-603. Epub 2006 Aug 1.

Navenot JM, Wang ZX, Peiper SC. Characterization of constitutively active mutants of G protein-coupled receptors. Methods Mol Biol. 2006;332:129-39.

Wang ZX, Broach JR, Peiper SC. Functional expression of CXCR4 in Saccharomyces cerevisiae in the development of powerful tools for the pharmacological characterization of CXCR4. Methods Mol Biol. 2006;332:115-27.

Sui Y, Yang Z, Xiong S, Zhang L, Blanchard KL, Peiper SC, Dynan WS, Tuan D, Ko L. Abstract Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers. Oncogene. 2006 Jul 31; [Epub ahead of print] .

Tamamura H, Tsutsumi H, Masuno H, Mizokami S, Hiramatsu K, Wang Z, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Fujii N. Abstract Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs. Org Biomol Chem. 2006 Jun 21;4(12):2354-7. Epub 2006 May 12.

Napier KB, Wang ZX, Peiper SC, Trent JO. CCR5 interactions with the variable 3 loop of gp120. J Mol Model (Online). 2006 May 24; [Epub ahead of print].

Niida A, Tanigaki H, Inokuchi E, Sasaki Y, Oishi S, Ohno H, Tamamura H, Wang Z, Peiper SC, Kitaura K, Otaka A, Fujii N. Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists. J Org Chem. 2006 May 12;71(10):3942-51..

Tamamura H, Esaka A, Ogawa T, Araki T, Ueda S, Wang Z, Trent JO, Tsutsumi H, Masuno H, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N. Abstract Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds. Org Biomol Chem. 2005 Dec 21;3(24):4392-4. Epub 2005 Nov 15.