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   Qinwen Mao, MD,PhD
   Assistant Professor of Pathology          
   Olson 2-459
   710 N. Fairbanks  
   Chicago, IL  60611

   q-mao@northwestern.edu  

Phone:  (312) 926-9487
Fax:  (312) 926-9830  

Anatomic Pathology Division
Neuropathology  

Medical School

Fourth Military Medical University, China, MD and PhD

Site of Residency

University of Texas Southwestern Medical School

Site of Fellowship

University of Texas Southwestern Medical School

Selected Publications

Xia H, Mao Q (co-first author), Davidson BL. The HIV tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors. Nat Biotechnology 19:640-644, 2001

Xia H, Mao Q (co-first author), Paulson H, Davidson BL. SiRNA-mediated gene silencing in vitro and in vivo. Nat Biotechnology 20:1006-1010, 2002.

Mao Q, Foster BJ, Xia H, Davidson BL. Membrane topology of CLN3, the protein underlying Batten disease. FEBS Lett. 541:40-46, 2003.

Xia H, Mao Q (co-first author), Eliason SL, Harper SQ, Martins IH, Orr HT, Paulson HL, Yang L, Kotin RM, Davidson BL RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nat Medicine 10: 816-820, 2004.

Harper SQ, Staber PD, He X, Eliason SL, Martins IH, Mao Q, Yang L, Kotin RM, Paulson HL, Davidson BL. RNA interference improves motor and neuropathological abnormalities in a Huntington’s disease mouse model. PNAS 102:5820-5825, 2005.

Passini MA, Dodge JC, Bu J, Yang W, Zhao Q, Sondhi D, Hackett NR, Kaminshy SM, Mao Q, Shihabuddin LS, Cheng SH, Sleat DE, Stewart GR, Davidson BL, Lobel P, Crystal RG. Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis. J Neurosci 26: 1334-1342, 2006

Eliason SL, Stein CS, Mao Q, Tecedor L, Ding S, Gaines DM, Davidson BL. A knock-in reporter model of Batten’s disease. J Neurosci 27: 9826-9834, 2007.

Liu S, Mao Q, Zhang W, Zheng X, Bian Y, Wang D, Li H, Chai L, Zhao J, Xia H. Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells. Biosci Rep 29:103-109, 2009.
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