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Xiao-Di Tan, MD
Children's Memorial Hospital
Associate Professor of Pathology, Feinberg School of Medicine, Northwestern University
Eloise and Warren Batts Research Scholar
2300 Children's Plaza Box 217
Chicago, IL 60614
xtan@northwestern.edu
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Phone: (773) 755-6380
Fax: (773) 755-6581
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Medical School
West China University of Medical Sciences, Sichuan, P. R. China, 1983
Site of Residency
Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 1988
Site of Fellowship
The Feinberg School of Medicine (Northwestern University), Chicago, IL, 1991
Research Interests
Mucosal immunology and innate immunity. Pathogenesis of intestinal injury. Intestinal epithelial biology and inflammation.
Selected Publications
 Tan
XD, Chen YH, Liu QP, Gonzalez-Crussi F, Liu XL. Prostanoids mediate
the protective effect of trefoil factor 3 in oxidant-induced epithelial cell injury:
role of cyclooxygenase-2. J. Cell Sci. 2000 113:2149-2155
Chen
YH, Lu Y, De Plaen IG, Wang LY, Tan XD. Transcription factor
NF-?B signals anti-anoikic effect of trefoil factor 3 in intestinal epithelial
cells. Biochem. Biophys. Res. Commun. 2000. 274:57682
De
Plaen IG, Qu XD, Wang H, Tan XD, Wang LY, Han XB, Rozenfeld RA,
Hsueh W. Endotoxin, but not platelet-activating factor, activates nuclear
factor ?B and increases I?B? and I?B? turnover in enterocytes. Immunology 2002.
106:577-83
Hsueh
W, Caplan MS, Qu XW, Tan XD, De Plaen IG, and GonzalezCrussi
F. Neonatal necrotizing enterocolitis: clinical considerations and pathogenetic
concepts. Pediatr. Dev. Pathol. 2003. 6:6-23.
Zhu
YQ, Lu Y, Tan XD. Monochloramine induces reorganization
of nuclear speckles and phosphorylation of SRp30 in human colonic epithelial cell:
Role of protein kinase C. Am. J. Physiol.:Cell Physiol. 2003. 285:C1294-303
Recommended Resources
American Gastroenterological Association, American Physiological Society
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