Northwestern University Feinberg School of Medicine

Department of Pathology

Resident Research at Northwestern

    

While not a formal requirement, research is an important component of the residency experience at Northwestern.  Guaranteed funding and salary support for 18 months or more of dedicated research time is provided to trainees in the physician scientist training program (PSTP).  For non-PSTP residents, funding for research is available through an internal grant review process where residents submit proposals under the supervision of faculty mentors.   All residents receive 4 months of elective time during their residency.  At the discretion of the resident and program director, some or all of this elective time can be used for research in a variety of settings, ranging from clinical to translational to basic science.

Recent research awards received by our residents:

The Women Faculty Organization Award for Excellence in Women’s Health Research (Clinical Research/Education/Public Health category), Feinberg School of Medicine Fourteenth Annual Lewis Landsberg Research Day: “Histologic and Molecular Analysis of Hydropic Leiomyoma: A Variant of Leiomyoma Closely Related to HMGA2 Overexpression,” Brannan Griffin MD, Xiuhua Xu PhD, Xinyan Lu MD, and Jian-Jun Wei MD.

3rd place, Chicago Pathology Society Resident Research Competition: “Mutation spectrum of KRAS gene in colorectal adenocarcinomas using next generation sequencing: a single institution large cohort.” Ryan Jones MD PhD, Andrew Bandy MD, Audrey Deeken-Draisey MD, Jie Liao, MD, Leyu Sun, Juehua Gao MD PhD, Guang-Yu Yang MD PhD. February 2018

2nd place, Chicago Pathology Society Resident Research Competition “Reflex Alternate Reference Probe D17S122 in Double (IHC and FISH) Equivocal Invasive Breast Carcinomas May Aid in Establishing True HER2 Status” Brannan Griffin MD, Jennifer Pincus MD, Kalliopi P. Siziopikou MD PhD and Luis Z. Blanco Jr. MD. February 2017

1st place, International Society of Dermatopathology Trainee World Cup "Genomic Assessment of Blitz Nevi Suggests Classification as a Subset of Blue Nevus Rather Than Spitz Nevus: Clinical, Histopathologic, and Molecular Analysis of 18 Cases.” Christina Isales MD, Pedram Gerami MD. 2017

Best Poster Award, 20th Joint Meeting of the International Society of Dermatopathology “Microcystic Adnexal Carcinoma Presenting as a Subareolar Breast Mass with Lung Metastasis: A Rare Presentation with Next Generation Sequencing Mutations.” Tim Tan MD, Megan Sullivan MD, Joan Guitart MD, Luis Blanco.  March 2017

​3rd Place Award, American Society of Dermatopathology Duel of Dermatopathology Abstract Competition, “Eccrine Syringofibroadenoma in Association with Acquired Epidermodysplasia Verruciformis.” Tim Tan MD, Joan Guitart MD, Liu L, Brieva JC, Amin S, Rani M, Pedram Gerami MD, Pedram Yazdan MD. October 2016

Best Poster Award, 19th Joint Meeting of the International Society of Dermatopathology. “Elastic Staining in Differentiating Between Follicular Streamers and Follicular Scars in Horizontal Scalp Biopsy Sections” Tim Tan MD, Joan Guitart MD, Pedram Gerami MD, Pedram Yazdan MD. March 2016

Recent peer reviewed publications by our residents (2014-2017)

1: Griffin B, Pincus J, Siziopikou KP, Blanco LZ Jr. Double equivocal HER2 invasive breast carcinomas: institutional experience and review of literature. ​​Archives of Pathology and Laboratory Medicine. Accepted Sept 2017.

2: Griffin B, George D, Jennings L, Chou P, Arva N. Malignant Ectomesenchymoma: Series Analysis of a Histologically and Genetically Heterogeneous Tumor​. International Journal of Surgical Pathology. Accepted Sept 2017.

3: Hakar M, Chandler JP, Bigio EH, Mao Q. Neuroendocrine carcinoma of the pineal parenchyma. The first reported case. J Clin Neurosci. 2017 Jan;35:68-70.

4: Isales MC, Haugh AM, Bubley J, Verzì AE, Zhang B, Kudalkar E, Lee CY, Yazdan P, Guitart J, Gerami P. Genomic Assessment of Blitz Nevi Suggests Classification  as a Subset of Blue Nevus Rather Than Spitz Nevus: Clinical, Histopathologic, and Molecular Analysis of 18 Cases. Am J Dermatopathol. 2017 Apr 27.

5: Tan T, Guitart J, Gerami P, Yazdan P. Elastic Staining in Differentiating Between Follicular Streamers and Follicular Scars in Horizontal Scalp Biopsy Sections. Am J Dermatopathol. 2017 Aug 9.

6: Poropatich K, Fontanarosa J, Swaminathan S, Dittmann D, Chen S, Samant S, Zhang B. Comprehensive T cell immunophenotyping and next generation sequencing from HPV-positive and -negative head and neck squamous cell carcinomas. J Pathol. 2017 Aug 3.

7: Poropatich K, Fontanarosa J, Samant S, Sosman JA, Zhang B. Cancer Immunotherapies: Are They as Effective in the Elderly? Drugs Aging. 2017 Aug;34(8):567-581.

8: Poropatich K, Hernandez D, Fontanarosa J, Brown K, Woloschak G, Paintal A, Raparia K, Samant S. Peritumoral cuffing by T-cell tumor-infiltrating lymphocytes distinguishes HPV-related oropharyngeal squamous cell carcinoma from oral cavity  squamous cell carcinoma. J Oral Pathol Med. 2017 Jun 20.

9: Poropatich K, Dittmann D, Chen YH, Raparia K, Wolniak K, Gao J. A Small Case Series of Intravascular Large B-Cell Lymphoma with Unexpected Findings: Subset of Cases with Concomitant Extravascular Central Nervous System (CNS) Involvement Mimicking Primary CNS Lymphoma. J Pathol Transl Med. 2017 May;51(3):284-291.

10: Poropatich K, Yang JC, Goyal R, Parini V, Yang XJ. Nuclear size measurement for distinguishing urothelial carcinomas from reactive urothelium on tissue sections. Diagn Pathol. 2016 Jun 30;11(1):57.

11: Parimi V, Goyal R, Poropatich K, Yang XJ. Neuroendocrine differentiation of prostate cancer: a review. Am J Clin Exp Urol. 2014 Dec 9;2(4):273-85. eCollection 2014. Review.

12: Reyes MC, Huang X, Bain A, Ylagan L. Primary pancreatic leiomyosarcoma with metastasis to the liver diagnosed by endoscopic ultrasound-guided fine needle aspiration and fine needle biopsy: A Case Report and Review of Literature. Diagn  Cytopathol. 2016 Dec;44(12):1070-1073.

13: Lewis N, Blanco LZ Jr, Maniar KP. p16 Expression and Biological Behavior of Flat Vulvar Low-grade Squamous Intraepithelial Lesions (LSIL). Int J Gynecol Pathol. 2017 Sep;36(5):486-492.

14: Ernst LM, Linn RL, Minturn L, Miller ES. Placental Pathologic Associations With Morbidly Adherent Placenta: Potential Insights Into Pathogenesis. Pediatr Dev Pathol. 2017 Sep-Oct;20(5):387-393.

15: Ernst LM, Linn RL, Minturn L, Miller ES. Placental Pathologic Associations with Morbidly Adherent Placenta: Potential insights into Pathogenesis. Pediatr Dev Pathol. 2016 Jul 21.

16: Linn RL, Miller ES, Lim G, Ernst LM. Adherent basal plate myometrial fibers in the delivered placenta as a risk factor for development of subsequent placenta accreta. Placenta. 2015 Dec;36(12):1419-24.

17: Edelstein AI, Linn RL, Fritsch MK, Sagan M. Osteochondroma With Contiguous Bronchogenic Cyst of the Scapula. Am J Orthop (Belle Mead NJ). 2015 Sep;44(9):E355-7.

18: Miller ES, Minturn L, Linn R, Weese-Mayer DE, Ernst LM. Stillbirth evaluation: a stepwise assessment of placental pathology and autopsy. Am J Obstet Gynecol. 2016 Jan;214(1):115.e1-6. doi: 10.1016/j.ajog.2015.08.049. Epub 2015 Aug 28.

19: Miller ES, Linn RL, Ernst LM. Does the presence of placental basal plate myometrial fibres increase the risk of subsequent morbidly adherent placenta: a case-control study. BJOG. 2016 Dec;123(13):2140-2145.

20: Ernst LM, Rand CM, Bao R, Andrade J, Linn RL, Minturn L, Zhang C, Kang W, Weese-Mayer DE. Stillbirth: Genome-wide copy number variation profiling in archived placental umbilical cord samples with pathologic and clinical correlation. Placenta. 2015 Aug;36(8):783-9.

21: Linn RL, Minturn L, Yee LM, Maniar K, Zhang Y, Fritsch MK, Kashireddy P, Kapur R, Ernst LM. Placental mesenchymal dysplasia without fetal development in a twin gestation: a case report and review of the spectrum of androgenetic biparental mosaicism. Pediatr Dev Pathol. 2015 Mar-Apr;18(2):146-54.

22: Linn RL, Kiley J, Minturn L, Fritsch MK, Dejulio T, Rostlund E, Ernst LM. Recurrent massive perivillous fibrin deposition in the placenta associated with fetal renal tubular dysgenesis: case report and literature review. Pediatr Dev Pathol. 2013 Sep-Oct;16(5):378-86.

23: Chouhan JD, Chu DI, Birs A, Pyle LC, Van Batavia JP, Linn RL, Back SJ, Russo  P, Darge K, Kolon TF, Srinivasan AK. Ovotestis in Adolescence: 2 Case Reports. Urology. 2017 Jul;105:171-174.

24: Virk RK, Abro S, de Ubago JMM, Pambuccian SE, Quek ML, Wojcik EM, Mehrotra S, Chatt GU, Barkan GA. The value of the UroVysion® FISH assay in the risk-stratification of patients with "atypical urothelial cells" in urinary cytology specimens. Diagn Cytopathol. 2017 Jun;45(6):481-500.

25: Ubago JM, Zhang Q, Kim JJ, Kong B, Wei JJ. Two Subtypes of Atypical Leiomyoma: Clinical, Histologic, and Molecular Analysis. Am J Surg Pathol. 2016 Jul;40(7):923-33.

26: Abboud S, Raparia K, Ubago JM, Resnick S. AngioVac extraction of intra-atrial hepatoma masquerading as PICC-associated thrombus. Diagn Interv Radiol. 2016 Jan-Feb;22(1):72-4.

27: Zhang Q, Ubago J, Li L, Guo H, Liu Y, Qiang W, Kim JJ, Kong B, Wei JJ. Molecular analyses of 6 different types of uterine smooth muscle tumors: Emphasis in atypical leiomyoma. Cancer. 2014 Oct 15;120(20):3165-77.

28: Lin X, Davion S, Bertsch EC, Omar I, Nayar R, Laskin WB. Federation Nationale des Centers de Lutte Contre le Cancer grading of soft tissue sarcomas on needle core biopsies using surrogate markers. Hum Pathol. 2016 Oct;56:147-54.

29: Bertsch EC, Minturn L, Gotteiner NL, Ernst LM. Absent Aortic Valve in DiGeorge Syndrome. Pediatr Dev Pathol. 2016 Jan-Feb;19(1):61-3.

30: Bertsch E, Qiang W, Zhang Q, Espona-Fiedler M, Druschitz S, Liu Y, Mittal K, Kong B, Kurita T, Wei JJ. MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma and leiomyosarcoma. Mod Pathol. 2014 Aug;27(8):1144-53. 

31: Kane JR, Lewis N, Lin R, Villa C, Larson A, Wayne JD, Yeldandi AV, Laskin WB. Plexiform fibromyxoma with cotyledon-like serosal growth: A case report of a rare gastric tumor and review of the literature. Oncol Lett. 2016 Mar;11(3):2189-2194.

32: Kashireddy P, Larson A, Minturn L, Ernst L. Case Report of Autopsy and Placental Examination After Radiofrequency Ablation of an Acardiac Twin. Lab Med. 2015 Summer;46(3):248-53.