Northwestern University Feinberg School of Medicine

Department of Pathology

Guang-Yu  Yang, MD, PhD

Guang-Yu Yang, MD, PhD

Joseph C. Calandra Research Professor of Pathology and Toxicology

Professor of Pathology

Focus of Work

Bio

Surgical Pathology<BR><BR>
The long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are 1) to develop a molecular mimicking model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcin...[Read full text]
Surgical Pathology<BR><BR>
The long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are 1) to develop a molecular mimicking model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcinogenesis; 2) to study the pathogenesis and molecular biomarkers of pancreatic carcinoma in genetically engineered mouse model and in human; and 3) to develop an efficient strategy on the prevention of chronic inflammation-driven carcinogenesis, particularly interested in dietary nutrients, antioxidants, green tea and inositol compounds and specifically targeted on colorectal, pancreatic, and liver carcinogenesis.[Shorten text]

Keywords

Select a keyword to see all related Feinberg faculty via the main faculty profile site.


Education and Certification

  • MD: China Medical University (1983)
  • PhD: China Medical University, Molecular Pathology (1992)
  • Residency: New York University Medical Center (2004)
  • Fellowship: Johns Hopkins Hospital (2005)
  • Board Certification: Anatomic Pathology & Clinical Pathology

Contact

312-503-0645
312-926-5832

Ward Building Room Ward 4-115
303 E Chicago Avenue
Chicago IL 60611