Northwestern University Feinberg School of Medicine

Department of Pathology



Clinical Chemistry is a discipline of Clinical Pathology that is devoted to analysis of bodily fluids, especially blood and urine. Methods used in the NMH Clinical Chemistry Laboratory include centrifugal, spectral, electrochemical, chromato-graphic, electrophoretic, and immunologic techniques.


During their training, Pathology residents rotate through the Clinical Chemistry Division for no less than two months.  During their time in the Division, residents have bench assignments and they meet regularly with the Medical Director, Greg Retzinger, MD, PhD, for both didactic sessions and patient care rounds. A host of topics pertinent to the discipline are covered, including appropriate utilization of tests, divisional quality assurance, proficiency testing, new test validation, instrument evaluation and purchase, and basic principles applicable to organ- and/or disease-specific testing.


The Clinical Chemistry Division of the NMH Clinical Laboratory serves as the central testing facility for a number of extramurally funded research projects, including both national and international ones. The Division also routinely serves as a beta testing site for some of the newest technologies being applied to analysis of patient samples.

Patient Care

Testing done in the Clinical Chemistry Division of the NMH Clinical Laboratory is used to monitor the levels of hundreds of different health- and/or disease-related analytes.  Because the Clinical Chemistry Laboratory analyzes large numbers of patient samples, it is highly automated. Exceptional quality control is characteristic. Data generated in the clinical chemistry laboratory are used to monitor a patient’s health status, disease progression, drug levels and response to treatment.

Chemistry Faculty

Dr. Gregory Retzinger, Chemistry Faculty

Gregory S Retzinger, MD, PhD
Medical Director, Chemistry