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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department's investigations below.

We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research

Peng Ji, MD, PhD, headshot
Two women in a lab handling liquids

Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease to develop new and improved strategies to diagnose and treat inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Explore Our Research Areas

Affiliated Research Centers & Institutes

Our department faculty conduct research within the department and across Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrates the importance we place on scientific collaboration.

Research Cores

Core facilities provide cost-effective access to state-of-the-art equipment, the latest technologies and expert technical advice for individual scientists.

Pathology Core Facility

The Pathology Core Facility is a centralized, comprehensive laboratory providing histology, immunohistochemistry, molecular analysis, extraction and microscopic evaluation services for human tissue-based studies.

About Pathology Core Facility

Mouse Histology & Phenotyping Laboratory

The Mouse Histology & Phenotyping Laboratory (MHPL) assists primary investigators and scientists with standard and customized research-specific histology services.

About MHPL

Skin Biology and Diseases Resource-Based Center

The Skin Biology and Diseases Resource-Based Center (SBDRC) promotes outstanding bench and clinical research in cutaneous biology to improve patient care.

About SBDRC

Explore Recent Publications

Efineptakin alfa (NT-I7) improves overall survival and induces immune niches in murine tumors.

Dinh T, Lee J, Islam S, Nanda N, Bjelivuk D, Andrews D, Zhang J, Mani NL, Zhou J, Wolfarth AA

Genes Dis 2027 Jan;14(1):102136. pii:102136

Sirt1 transgene delivery improves diabetes-impaired wound healing.

Luo R, Wang H, Duan C, Jen M, Kuo HY, Wang X, Mrksich M, Ameer G

Bioact Mater 2026 Nov;65:521-534. doi:10.1016/j.bioactmat.2026.06.007

Therapy-associated lineage plasticity in DIPG following combined CDK4/6 inhibitor, temozolomide, and radiation.

Huang ZL, Jiang T, Suarez Palacios MM, Ouyang T, Abdallah A, Niu L, Chen J, Zhai X, Ciolak E, Qiang W

Cancer Lett 2026 Oct 28;659:218771. doi:10.1016/j.canlet.2026.218771

Adolescent health across Asia Pacific, 2000-23: a systematic analysis for the Global Burden of Disease Study 2023.

Lancet Child Adolesc Health 2026 Oct;10(10):731-754. doi:10.1016/S2352-4642(26)00163-X

Retraction notice to "Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc" [Redox Biol. 13 (2017) 482-497].

Yang S, Zhao L, Han Y, Liu Y, Chen C, Zhan M, Xiong X, Zhu X, Xiao L, Hu C

Redox Biol 2026 Oct;96:104362. pii:104362

NRF2-mediated ferroptosis suppression defines a cancer-specific vulnerability in tumors.

Huang D, Zhang M, Stansfield BN, Ahmed M, Xu T, Alexander L, Anandhan A, Ma M, Liu P, Yang-Hartwich Y

Redox Biol 2026 Oct;96:104352. pii:104352

Outcomes of Children With Orbital Rhabdomyosarcoma, 1991-2016: A Report From the International Soft Tissue Sarcoma Consortium (INSTRuCT).

Metts J, Anderson J, Vokuhl C, Koscielniak E, Urla C, Venkatramani R, Breneman J, Bradley J, Arnold M, Minard-Colin V

Pediatr Blood Cancer 2026 Oct;73(10):e70613. doi:10.1002/1545-5017.70613

Concordance Between Institutional and Central Pathology, Surgery, and Radiology Reviews on the Children's Oncology Group AREN03B2 Renal Tumor Biology and Classification Study.

Mullen EA, Renfro LA, Ehrlich PF, Khanna G, Gratias EJ, Cost NG, Parsons LN, Grundy PE, Fernandez CV, Geller JI

Pediatr Blood Cancer 2026 Oct;73(10):e70515. doi:10.1002/1545-5017.70515

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