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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Research Resources

Recent Publications

NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomas.

Sadagopan NS, Gomez M, Tripathi S, Billingham LK, DeLay SL, Cady MA, Congivaram HTS, Chia TY, Wan H, Wang S, Raleigh DR, Kaluba FC, Lien EC, Heimberger AB, Lee-Chang C, Youngblood MW, Magill ST, Miska JM.

J Neurooncol. 2025 Dec;175(3):979-991. doi: 10.1007/s11060-025-05208-5. Epub 2025 Sep 9.

Adaptation and changing phenotypes through transgenerational epigenetics.

Van Winkle LJ, Ryznar RJ, Iannaccone PM.

Epigenetics. 2025 Dec;20(1):2460246. doi: 10.1080/15592294.2025.2460246. Epub 2025 Aug 13.

Life-course socioeconomic position and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Batalha MA, LeCroy MN, Lin J, Peters BA, Qi Q, Wang Z, Wang T, Gallo LC, Talavera GA, McClain AC, Thyagarajan B, Daviglus ML, Hou L, Llabre M, Cai J, Kaplan RC, Isasi CR.

Gut Microbes. 2025 Dec;17(1):2479772. doi: 10.1080/19490976.2025.2479772. Epub 2025 Mar 18.

Nivolumab in combination with R-CHOP for treatment-naïve diffuse large B-cell lymphoma: an evaluation of safety and efficacy.

Odetola O, Ma S, Winter J, Pro B, Roy I, Xie P, Zhang B, Chen Q, Koulogeorgas GP, Mi X, Chen R, Ma Y, Tang X, Bayer R, Eisner R, Nelson V, Shaikh H, Tsarwhas D, Saghir F, Venugopal P, Gordon LI, Karmali R.

Blood Adv. 2025 Nov 11;9(21):5616-5625. doi: 10.1182/bloodadvances.2025016298.

Reflecting on Scientific Growth and Innovation as the Society for Neuro-Oncology Turns 30.

De La Fuente MI, Brastianos PK, Gampel B, Nassiri F, Raleigh DR, Ida CM, Abdelbaki MS, Pekmezci M, Bagley S, Young JS, Lukas RV, Hirbe AC, Ellingson BM, Villanueva-Meyer J, Lasorella A, Sarkaria JN, Gutmann DH, Haas-Kogan D, Galanis E, Chang SM.

Neuro Oncol. 2025 Nov 4:noaf255. doi: 10.1093/neuonc/noaf255. Online ahead of print.

Reply to Singer: Strike paper mills at the root.

Richardson RAK, Hong SS, Byrne JA, Stoeger T, Amaral LAN.

Proc Natl Acad Sci U S A. 2025 Nov 4;122(44):e2524787122. doi: 10.1073/pnas.2524787122. Epub 2025 Oct 27.

High Blood Pressure in Childhood and Premature Cardiovascular Disease Mortality.

Freedman AA, Perak AM, Ernst LM, Borders A, Miller GE, Allen NB, Gilman SE, Khan SS.

JAMA. 2025 Nov 4;334(17):1555-1557. doi: 10.1001/jama.2025.14405.

Burden of Central Nervous System Cancer in the United States, 1990-2021.

GBD 2021 US CNS Cancer Collaborators; Han HJ, Kim YS, Park S, Shin JI, Kim MS, Moon JH, Kim YB, Ababneh HS, Abu-Zaid A, Areda D, Arul S, Azzam AY, Bardhan M, Bayat Tork MA, Behnam B, Bilgin GB, Bhardwaj PV, Bhuyan SS, Lomer NB, Chen MX, Chennapragada SS, Dai X, Dean FE, Deekonda S, Ding X, Doshi OP, E'mar AR, Elhadi M, Fares J, Fazeli P, Fisher JL, Fotouhi M, Gholamrezanezhad A, Ida F, Iwu CD, Jalloh M, Jani CT, Kalani R, Kankam SB, Kazemi F, Keshwani A, Khosla AA, Lim SS, Mehboob R, Mestrovic T, Mokdad AH, Murray CJL, Naik G, Natto ZS, Nguyen D, Nugen F, Orscelik A, Parikh RR, Penberthy L, Pestell RG, Prabhu D, Puvvula J, Ramasamy SK, Sabet CJ, Schumacher AE, Senol YC, Sham S, Sherchan SP, Simegn GL, Singh JA, Solanki R, Srichawla BS, Taiba J, Tanwar M, Amirikah MT, Verma A, Yunusa I, Zheng DX, Yon DK, Park KY.

JAMA Neurol. 2025 Nov 3:e254286. doi: 10.1001/jamaneurol.2025.4286. Online ahead of print.

Intrinsic MicroRNA-10a Restricts Regulatory T Cell Suppressive Function and Intestinal Repair by Coordinating Transcriptional, Metabolic, and Epithelial Repair Pathways.

Yang W, Yu T, Yang H, Yao S, Ma R, Steinert EM, Ridge KM, Cui W, Chandel NS, Cong Y.

Adv Sci (Weinh). 2025 Nov 3:e09953. doi: 10.1002/advs.202509953. Online ahead of print.

Modeling the Relationship Between Listener Factors and Envelope Fidelity: A Pooled Analysis Spanning a Decade.

Rallapalli V, Crukley J, Lundberg E, Kates JM, Arehart K, Souza P.

Ear Hear. 2025 Nov 3. doi: 10.1097/AUD.0000000000001754. Online ahead of print.

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