Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs via the descriptions below.

Carcinogensis/Neoplasia

Cell and Developmental Pathology

Inflammation/Immnology

Neuropathology

Areas of Research

Affilated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Recent Publications

WNT pathway mutations in metachronous oligometastatic castration-sensitive prostate cancer.

Sutera P, Deek MP, Van der Eecken K, Shetty AC, Chang JH, Hodges T, Song Y, Verbeke S, Van Dorpe J, Fonteyne V, De Laere B, Mishra M, Rana Z, Molitoris J, Ferris M, Ross A, Schaeffer E, Roberts N, Song DY, DeWeese T, Pienta KJ, Antonarakis ES, Ost P, Tran PT.

Int J Radiat Oncol Biol Phys. 2023 Jan 25:S0360-3016(22)03628-8. doi: 10.1016/j.ijrobp.2022.12.006. Online ahead of print.

Storage differentially impacts alloimmunization to distinct red cell antigens following transfusion in mice.

Maier CL, Jajosky RP, Patel SR, Verkerke HP, Fuller MD, Allen JW, Zerra PE, Fasano RM, Chonat S, Josephson CD, Gibb DR, Eisenbarth SC, Luckey CJ, Hudson KE, Hendrickson JE, Arthur CM, Stowell SR.

Transfusion. 2023 Jan 27. doi: 10.1111/trf.17251. Online ahead of print.

Cytomorphology of renal angiomyolipoma: performance and accuracy of touch preparation of core needle biopsy.

Gelarden IA, Gama A, Choy B.

J Am Soc Cytopathol. 2023 Jan 3:S2213-2945(22)00288-5. doi: 10.1016/j.jasc.2022.12.003. Online ahead of print.

Variant allelic frequency of driver mutations predicts success of genomic DNA methylation classification in central nervous system tumors.

Jamshidi P, McCord M, Galbraith K, Santana-Santos L, Jennings LJ, Snuderl M, Horbinski C.

Acta Neuropathol. 2023 Jan 26. doi: 10.1007/s00401-023-02542-8. Online ahead of print.

No difference in anti-spike antibody and surrogate viral neutralization following SARS-CoV-2 booster vaccination in persons with HIV compared to controls (CO-HIV Study).

Kling KD, Janulis P, Demonbreun AR, Sancilio A, Berzins B, Krueger K, Achenbach C, Price R, Sullivan M, Caputo M, Hockney S, Zembower T, McDade TW, Taiwo B.

Front Immunol. 2023 Jan 9;13:1048776. doi: 10.3389/fimmu.2022.1048776. eCollection 2022.

A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature.

Kazenwadel J, Venugopal P, Oszmiana A, Toubia J, Arriola-Martinez L, Panara V, Piltz SG, Brown C, Ma W, Schreiber AW, Koltowska K, Taoudi S, Thomas PQ, Scott HS, Harvey NL.

Nature. 2023 Jan 25. doi: 10.1038/s41586-022-05650-9. Online ahead of print.

IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity.

Kim D, Rai NK, Burrows A, Kim S, Tripathi A, Weinberg SE, Dutta R, Sen GC, Min B.

J Immunol. 2023 Jan 25:ji2200746. doi: 10.4049/jimmunol.2200746. Online ahead of print.

Sensitization in transplantation: Assessment of Risk 2022 Working Group Meeting Report.

Tambur AR, Bestard O, Campbell P, Chong AS, Barrio MC, Ford ML, Gebel HM, Heidt S, Hickey M, Jackson A, Kosmoliaptsis V, Lefaucheur C, Louis K, Mannon RB, Mengel M, Morris A, Pinelli DF, Reed EF, Schinstock C, Taupin JL, Valenzuela N, Wiebe C, Nickerson P.

Am J Transplant. 2023 Jan;23(1):133-149. doi: 10.1016/j.ajt.2022.11.009. Epub 2023 Jan 11.

Clinical recommendations for posttransplant assessment of anti-HLA (Human Leukocyte Antigen) donor-specific antibodies: A Sensitization in Transplantation: Assessment of Risk consensus document.

Lefaucheur C, Louis K, Morris AB, Taupin JL, Nickerson P, Tambur AR, Gebel HM, Reed EF; STAR 2022 Working Group.

Am J Transplant. 2023 Jan;23(1):115-132. doi: 10.1016/j.ajt.2022.11.013. Epub 2023 Jan 11.

Development and Validation of a Machine Learning Model for Detection and Classification of Tertiary Lymphoid Structures in Gastrointestinal Cancers.

Li Z, Jiang Y, Li B, Han Z, Shen J, Xia Y, Li R.

JAMA Netw Open. 2023 Jan 3;6(1):e2252553. doi: 10.1001/jamanetworkopen.2022.52553.

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