The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.
Message from the Vice Chair
"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."
Peng Ji, MD, PhD
Vice Chair of Research
Areas of Research
Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs via the descriptions below.
Affilated Research Centers and Institutes
The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.
Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.
Modulation of T cell function and survival by the tumor microenvironment.
Mani N, Andrews D, Obeng RC.
Front Cell Dev Biol. 2023 May 18;11:1191774. doi: 10.3389/fcell.2023.1191774. eCollection 2023.
Reworking Classification of First Branchial Cleft Anomalies.
Wilson J 4th, Jaju A, Wadhwani N, Gorelik M, Johnston D, Rastatter J, Bhushan B, Hazkani I, Fudyma I, Maddalozzo J.
Laryngoscope. 2023 Jun 5. doi: 10.1002/lary.30783. Online ahead of print.
Elevated expression of immune and DNA repair genes in mated queens and kings of the Reticulitermes chinensis termites.
Dong Y, Peng X, Hussain R, Niu T, Zhang H, Wang H, Xing LX, Wang R.
Exp Gerontol. 2023 Jun 2:112228. doi: 10.1016/j.exger.2023.112228. Online ahead of print.
The impact of HIV and ART exposure during pregnancy on fetal growth: a prospective study in a South African cohort.
Mtintsilana A, Norris SA, Dlamini SN, Nyati LH, Aronoff DM, Koethe JR, Goldstein JA, Prioreschi A.
BMC Pregnancy Childbirth. 2023 Jun 3;23(1):415. doi: 10.1186/s12884-023-05743-x.
Correlations Between Gastrointestinal Symptoms and Endoscopic-Histologic Disease Activity in Adults with Ulcerative Colitis.
Tse CS, Nguyen HP, Singh S, Dulai PS, Neill J, Le H, Valasek M, Dervieux T, Collins AE, Boland BS.
Dig Dis Sci. 2023 Jun 3. doi: 10.1007/s10620-023-07986-2. Online ahead of print.
Potential values of formalin-fixed paraffin-embedded tissues for intratumoral microbiome analysis in breast cancer.
Chang J, Li X, Xia Q, Yang S, Zhang H, Yang H.
Heliyon. 2023 May 19;9(6):e16267. doi: 10.1016/j.heliyon.2023.e16267. eCollection 2023 Jun.
Insights into the regulation of glomerular filtration rate by the Keap1-Nrf2 pathway.
Kidokoro K, Kadoya H, Cherney DZI, Kondo M, Wada Y, Umeno R, Kishi S, Nagasu H, Nagai K, Suzuki T, Sasaki T, Yamamoto M, Kanwar YS, Kashihara N.
Kidney360. 2023 Jun 2. doi: 10.34067/KID.0000000000000171. Online ahead of print.
Management and Outcomes of Wilms Tumor with Suprarenal Intravascular Extension: A Pediatric Surgical Oncology Research Collaborative Study.
Naik-Mathuria B, Utria AF, Ehrlich PF, Aldrink JH, Murphy AJ, Lautz T, Dasgupta R, Short SS, Lovvorn HN 3rd, Kim ES, Newman E, Lal DR, Rich BS, Piché N, Kastenberg ZJ, Malek MM, Glick RD, Petroze RT, Polites SF, Whitlock R, Alore E, Sutthatarn P, Chen SY, Wong-Michalak S, Romao RL, Al-Hadidi A, Rubalcava NS, Marquart JP, Gainer H, Johnson M, Boehmer C, Rinehardt H, Seemann NM, Davidson J, Polcz V, Lund SB, McKay KG, Correa H, Rothstein DH.
Ann Surg. 2023 Jun 2. doi: 10.1097/SLA.0000000000005921. Online ahead of print.
Macrophage-endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa.
Ren X, Manzanares LD, Piccolo EB, Urbanczyk JM, Sullivan DP, Yalom LK, Bui TM, Lantz C, Najem H, Dulai PS, Heimberger AB, Thorp EB, Sumagin R.
J Clin Invest. 2023 Jun 1:e170733. doi: 10.1172/JCI170733. Online ahead of print.
Correspondence on "Technical standards for the interpretation and reporting of constitutional copy-number variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics (ACMG) and the Clinical Genome Resource (ClinGen)" by Riggs et al.
Spurdle AB, Drackley A, Ing A, Tudini E, Yap KL, Tavtigian SV.
Genet Med. 2023 May 30:100868. doi: 10.1016/j.gim.2023.100868. Online ahead of print.