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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Research Resources

Recent Publications

Clinical Insights Into CASPR1 and CASPR1/Contactin-1 Complex Autoimmune Nodopathies.

Paramasivan NK, Basal E, LaFrance-Corey RG, Arlt FA, Klein CJ, Swart G, Mozammel A, Mauermann ML, Dyck PJB, Berini SE, Engelstad J, Bucelli R, Magda P, Pniak E, Nagar CP, Crockett CD, McKeon A, Mills JR, Dubey D.

Neurology. 2026 Mar 10;106(5):e214403. doi: 10.1212/WNL.0000000000214403. Epub 2026 Feb 6.

DOCK8 and STAT3 cooperate to restrain IgE-inducing T follicular helper cells.

Siniscalco ER, Fisher C, Lu MP, Grassmann JDS, Mack CD, Yaakoubi R, Jacobsen D, Chen Q, Lee D, Rajamanimuthu P, Simoneau T, Preece K, Gray P, Okada S, Boisson B, Kayaoglu B, Danielson J, Freeman AF, Casanova JL, Chatila TA, Su HC, Ma CS, Williams A, Eisenbarth SC, Gowthaman U.

J Exp Med. 2026 Mar 2;223(3):e20241707. doi: 10.1084/jem.20241707. Epub 2026 Jan 28.

Artificial Intelligence and Machine Learning in Health Care: Current Capabilities, Emerging Potential, and Future Directions.

Liebovitz D, Wu A, Reamer C, Vadasz B.

Med Clin North Am. 2026 Mar;110(2):307-327. doi: 10.1016/j.mcna.2025.07.011. Epub 2025 Dec 1.

Authors' Response to Silicosarcoidosis: Do We Really Need Hybrid Labels That May Undermine Occupational Disease Recognition?

Hua JT, Cool CD, Cohen RA, Rose CS.

Am J Ind Med. 2026 Mar;69(3):214-215. doi: 10.1002/ajim.70054. Epub 2026 Jan 8.

The Impact of Next-Generation Sequencing on Interobserver Agreement and Diagnostic Accuracy of Deep Penetrating Melanocytic Neoplasms.

Jeyakumar JE, Addo AK, Beydoun HM, Olivares S, Bahrami A, Balamurugan T, Barnhill RL, Blokx WAM, Busam KJ, Cerroni L, Cook M, de La Fouchardière A, Duncan LM, Elder DE, Ferguson P, Ferrara G, Johansson I, Ko JS, Kwon JE, Landman G, Lezcano C, Lowe L, Massi D, Messina J, Mihic-Probst D, Parker DC, Redpath M, Sargen MR, Scolyer RA, Shea CR, Tetzlaff M, Torres-Cabala C, Tron V, Xu X, Yeh I, Yun SJ, Zembowicz A, Gerami P.

J Cutan Pathol. 2026 Mar;53(3):293-301. doi: 10.1111/cup.70049. Epub 2025 Dec 23.

ASO Visual Abstract: Surgical Management and Outcomes in Pediatric Adrenocortical Carcinoma: A Pediatric Surgical Oncology Research Collaborative Study.

Srivatsa S, Aldrink JH, Haque MR, Murphy A, Gehle D, Halepota H, Newman EA, Williams K, Mattei P, Johnston WR, Hwang R, Lautz TB, Ayala SA, Piché N, Lemoine CP, Debertin J, Polites SF, Rothstein DH, Riehle KJ, Nchinda N, Malek MM, Rinehardt HN, Gestrich C, Castle SL, Lopez A, Mayes MS, Myers EK, Roach JP, Craig BT, Lal DR, Schuh J, Cromeens BP, Mannava SV, Austin MT, Mayon LK, Kastenberg ZJ, Wallace M, Alexander A, Stellon MA, Le HD, Joshi DS, Chidiac C, Rhee DS, Cameron D, Stetson A, Rich BS, Glick RD, Fialkowski EA, Fowler K, Fareh R, Brown EG, Doyle K, Abril P, Grant C, Dasgupta R, Boehmer C, Mansfield SA.

Ann Surg Oncol. 2026 Mar;33(3):2753-2754. doi: 10.1245/s10434-025-18869-3.

Surgical Management and Outcomes in Pediatric Adrenocortical Carcinoma: A Pediatric Surgical Oncology Research Collaborative Study.

Srivatsa S, Aldrink JH, Haque MR, Murphy A, Gehle D, Halepota H, Newman EA, Williams K, Mattei P, Johnston WR, Hwang R, Lautz TB, Ayala SA, Piché N, Lemoine CP, Debertin J, Polites SF, Rothstein DH, Riehle KJ, Nchinda N, Malek MM, Rinehardt HN, Gestrich C, Castle SL, Lopez A, Mayes MS, Myers EK, Roach JP, Craig BT, Lal DR, Schuh J, Cromeens BP, Mannava SV, Austin MT, Mayon LK, Kastenberg ZJ, Wallace M, Alexander A, Stellon MA, Le HD, Joshi DS, Chidiac C, Rhee DS, Cameron D, Stetson A, Rich BS, Glick RD, Fialkowski EA, Fowler K, Fareh R, Brown EG, Doyle K, Abril P, Grant C, Dasgupta R, Boehmer C, Mansfield SA.

Ann Surg Oncol. 2026 Mar;33(3):2712-2728. doi: 10.1245/s10434-025-18731-6. Epub 2025 Nov 20.

BCLC strategy for prognosis prediction and treatment recommendations: The 2026 update.

Reig M, Sanduzzi-Zamparelli M, Forner A, Rimola J, Ferrer-Fàbrega J, Burrel M, Garcia-Criado Á, Díaz A, Llarch N, Iserte G, Mollà M, Kelley RK, Galle PR, Mazzaferro V, Salem R, Sangro B, Singal AG, Vogel A, Yanagihara TK, Ayuso C, Torres F, Bruix J.

J Hepatol. 2026 Mar;84(3):631-654. doi: 10.1016/j.jhep.2025.10.020. Epub 2025 Oct 27.

Circulating cell-free DNA methylation biomarkers for hepatocellular carcinoma risk prediction in HIV-positive Nigerian population.

Zheng Y, Han J, Qu Y, Wang J, Joyce BT, Okeke E, Davwar PM, Duguru MJ, Nyam DP, Odeghe E, Oyeleke G, Lesi OA, Imade GE, Sulaimon AA, Hawkins C, Abdulkareem FB, Badmos K, Gursel DB, Wei JJ, Silas OA, Kocherginsky M, Kim KA, Sun Z, Achenbach CJ, Zhang X, Yang H, Sagay AS, Ogunsola FT, Murphy RL, Roberts LR, Hou L.

Int J Cancer. 2026 Mar 1;158(5):1281-1291. doi: 10.1002/ijc.70204. Epub 2025 Oct 23.

Clinical trials and quasi-experimental studies in the treatment of noninfectious retinal vasculitis: A systematic review from the International Uveitis Study Group (IUSG) Retinal Vasculitis Study (ReViSe) - Report 4.

Saboya-Galindo P, Cifuentes-González C, Rojas-Carabali W, Mejía-Salgado G, Le Tong Y, Putera I, Song XYR, Walter CFY, Shengjuan Z, Chan R, La Distia Nora R, Biswas J, Gangaputra S, Pulido JS, Kempen JH, Nguyen QD, de-la-Torre A, Gupta V, Rosenbaum JT, Agrawal R; REVISE-IUSG study group.

Surv Ophthalmol. 2026 Mar-Apr;71(2):545-559. doi: 10.1016/j.survophthal.2025.09.013. Epub 2025 Sep 20.

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