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Northwestern University Feinberg School of Medicine
Department of Pathology

Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs via the descriptions below.

Affilated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Recent Publications

CRISPR/Cas9-mediated grna gene knockout leads to neurodevelopmental defects and motor behavior changes in zebrafish.

Zhu J, Xu H, Song H, Li X, Wang N, Zhao J, Zheng X, Kim KY, Zhang H, Mao Q, Xia H.

J Neurochem. 2021 Jan 22. doi: 10.1111/jnc.15307. Online ahead of print.

Engineered antigen-specific regulatory T cells for autoimmune skin conditions.

Mukhatayev Z, Ostapchuk YO, Fang D, Le Poole IC.

Autoimmun Rev. 2021 Jan 18:102761. doi: 10.1016/j.autrev.2021.102761. Online ahead of print.

Genetic Evaluation of Nosocomial Candida auris Transmission.

Roberts SC, Zembower TR, Ozer EA, Qi C.

J Clin Microbiol. 2021 Jan 20:JCM.02252-20. doi: 10.1128/JCM.02252-20. Online ahead of print.

The hygiene hypothesis, the COVID pandemic, and consequences for the human microbiome.

Finlay BB, et al.

Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2010217118. doi: 10.1073/pnas.2010217118.

A clinical prediction model to assess risk for pancreatic cancer among patients with prediabetes.

Boursi B, Finkelman B, Giantonio BJ, Haynes K, Rustgi AK, Rhim AD, Mamtani R, Yang YX.

Eur J Gastroenterol Hepatol. 2021 Jan 18. doi: 10.1097/MEG.0000000000002052. Online ahead of print.

Seroprevalence and Correlates of SARS-CoV-2 Antibodies in Health Care Workers in Chicago.

Wilkins JT, et al.

Open Forum Infect Dis. 2020 Dec 9;8(1):ofaa582. doi: 10.1093/ofid/ofaa582. eCollection 2021 Jan.

Homologous recombination deficiency (HRD) score in germline BRCA2- versus ATM-altered prostate cancer.

Lotan TL, et al.

Mod Pathol. 2021 Jan 18. doi: 10.1038/s41379-020-00731-4. Online ahead of print.

Identification of a druggable protein-protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1.

Tong X, Xu D, Mishra RK, Jones RD, Sun L, Schiltz GE, Liao J, Yang GY.

J Biol Chem. 2020 Nov 21;296:100098. doi: 10.1074/jbc.RA120.014749. Online ahead of print.

Supercharging BRD4 with NUT in carcinoma.

Eagen KP, French CA.

Oncogene. 2021 Jan 15. doi: 10.1038/s41388-020-01625-0. Online ahead of print.

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