Coronavirus information for Feinberg.

Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs via the descriptions below.

Affilated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Recent Publications

B Cell Lymphomas of the GI Tract.

Small S, Barnea Slonim L, Williams C, Karmali R.

Curr Gastroenterol Rep. 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8.

Umbilical cord miRNAs to predict neonatal early onset sepsis.

Ernst LM, Mithal LB, Mestan K, Wang V, Mangold KA, Freedman A, Das S.

PLoS One. 2021 May 7;16(5):e0249548. doi: 10.1371/journal.pone.0249548. eCollection 2021.

Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue.

Rehring JF, Bui TM, Galán-Enríquez CS, Urbanczyk JM, Ren X, Wiesolek HL, Sullivan DP, Sumagin R.

Front Immunol. 2021 Apr 20;12:654259. doi: 10.3389/fimmu.2021.654259. eCollection 2021.

Electrospray Mediated Localized and Targeted Chemotherapy in a Mouse Model of Lung Cancer.

Ruzgys P, Böhringer S, Dokumaci AS, Hari Y, Schürch CM, Brühl F, Schürch S, Szidat S, Riether C, Šatkauskas S, Geiser T, Hradetzky D, Gazdhar A.

Front Pharmacol. 2021 Apr 20;12:643492. doi: 10.3389/fphar.2021.643492. eCollection 2021.

Paired-like homeobox gene (PHOX2B) nonpolyalanine repeat expansion mutations (NPARMs): genotype-phenotype correlation in congenital central hypoventilation syndrome (CCHS).

Zhou A, Rand CM, Hockney SM, Niewijk G, Reineke P, Speare V, Berry-Kravis EM, Zhou L, Jennings LJ, Yu M, Ceccherini I, Bachetti T, Pennock M, Yap KL, Weese-Mayer DE.

Genet Med. 2021 May 6. doi: 10.1038/s41436-021-01178-x. Online ahead of print.

Anti-beta 2 glycoprotein I IgA in the SLICC classification criteria dataset.

Elkhalifa M, Orbai AM, Magder LS, Petri M, Alarcón GS, Gordon C, Merrill J, Fortin PR, Bruce IN, Isenberg D, Wallace D, Nived O, Ramsey-Goldman R, Bae SC, Hanly JG, Sanchez-Guerrero J, Clarke AE, Aranow C, Manzi S, Urowitz M, Gladman DD, Kalunian K, Werth VP, Zoma A, Bernatsky S, Khamashta M, Jacobsen S, Buyon JP, Dooley MA, Vollenhoven RV, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim S, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG Jr.

Lupus. 2021 May 6:9612033211014248. doi: 10.1177/09612033211014248. Online ahead of print.

Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.

Le Coz C, Nguyen DN, Su C, Nolan BE, Albrecht AV, Xhani S, Sun D, Demaree B, Pillarisetti P, Khanna C, Wright F, Chen PA, Yoon S, Stiegler AL, Maurer K, Garifallou JP, Rymaszewski A, Kroft SH, Olson TS, Seif AE, Wertheim G, Grant SFA, Vo LT, Puck JM, Sullivan KE, Routes JM, Zakharova V, Shcherbina A, Mukhina A, Rudy NL, Hurst ACE, Atkinson TP, Boggon TJ, Hakonarson H, Abate AR, Hajjar J, Nicholas SK, Lupski JR, Verbsky J, Chinn IK, Gonzalez MV, Wells AD, Marson A, Poon GMK, Romberg N.

J Exp Med. 2021 Jul 5;218(7):e20201750. doi: 10.1084/jem.20201750. Epub 2021 May 5.

MRI Staging in an Evolving Management Paradigm for Rectal Cancer, From the AJR Special Series on Cancer Staging.

Kaur H, Gabriel H, Taggart M, Kang HC, Konishi T, Rauch GM, Krishnan S, Chang G.

AJR Am J Roentgenol. 2021 May 5. doi: 10.2214/AJR.21.25556. Online ahead of print.

Immediate impact of the COVID-19 pandemic on CTSA TL1 and KL2 training and career development.

McCormack WT, Bredella MA, Ingbar DH, Jackson RD, Meagher EA, Morris CD, Nagel JD, Pusek S, Rubio DM, Sandberg K, Schnaper HW, Tsevat J, Umans JG, McIntosh S.

J Clin Transl Sci. 2020 Jun 29;4(6):556-561. doi: 10.1017/cts.2020.504.

Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.

Breeze CE, Batorsky A, Lee MK, Szeto MD, Xu X, McCartney DL, Jiang R, Patki A, Kramer HJ, Eales JM, Raffield L, Lange L, Lange E, Durda P, Liu Y, Tracy RP, Van Den Berg D; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed MESA Multi-Omics Working Group, Evans KL, Kraus WE, Shah S, Tiwari HK, Hou L, Whitsel EA, Jiang X, Charchar FJ, Baccarelli AA, Rich SS, Morris AP, Irvin MR, Arnett DK, Hauser ER, Rotter JI, Correa A, Hayward C, Horvath S, Marioni RE, Tomaszewski M, Beck S, Berndt SI, London SJ, Mychaleckyj JC, Franceschini N.

Genome Med. 2021 Apr 30;13(1):74. doi: 10.1186/s13073-021-00877-z.

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