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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

Read Full Message

Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Research Resources

Recent Publications

RhoGEF Ect2 supports RhoA activity at cell-cell junctions through desmoplakin.

Zarkoob H, Kam CY, Koetsier JL, McCarthy E, Jaiganesh A, Kelsell DP, Sheikh F, Godsel LM, Green KJ.

Life Sci Alliance. 2026 Mar 12;9(6):e202503454. doi: 10.26508/lsa.202503454. Print 2026 Jun.

Reply by Authors.

Rowe SP, Murtazaliev S, Amindarolzarbi A, Sheikhbahaei S, Meyer AR, Javadi MS, Wood M, Kaufmann B, Goel R, Viglianti BL, Pavlovich CP, Singla N, Pierorazio PM, Baras AS, Epstein JI, Baraban E, Allaf ME, Solnes LB, Oldan JD, Patel HD, Gorin MA.

J Urol. 2026 May;215(5):587-588. doi: 10.1097/JU.0000000000004949. Epub 2026 Apr 9.

Survival after intensive therapy or clofarabine in fit older adults with acute myeloid leukemia: E2906 phase 3 trial.

Foran JM, Sun Z, Luger SM, Claxton DF, Lazarus HM, Arber DA, Rowe JM, Paietta E, Racevskis J, Garrett-Bakelman F, Zhang Y, Altman JK, Al-Kali A, Zheng H, Pratz KW, Broun ER, Powell BL, O'Dwyer KM, Godwin JE, Ofran Y, Litzow MR, Tallman MS.

Blood Neoplasia. 2026 Jan 14;3(2):100194. doi: 10.1016/j.bneo.2026.100194. eCollection 2026 May.

Concurrent driver mutations induce distinct tumour morphologies on radiological imaging.

Rodríguez Sánchez DI, Vanneste T, Middelkoop J, Maxouri O, Rostami S, Ursprung S, Boveradze N, Chupetlovska K, Castagnoli F, Landolfi F, Hong EK, Pizzi AD, Gennaro N, Snaebjornsson P, Bodalal Z, Beets-Tan R.

Eur J Radiol. 2026 May;198:112738. doi: 10.1016/j.ejrad.2026.112738. Epub 2026 Feb 18.

Reply by Authors.

Rowe SP, Murtazaliev S, Amindarolzarbi A, Sheikhbahaei S, Meyer AR, Javadi MS, Wood M, Kaufmann B, Goel R, Viglianti BL, Pavlovich CP, Singla N, Pierorazio PM, Baras AS, Epstein JI, Baraban E, Allaf ME, Solnes LB, Oldan JD, Patel HD, Gorin MA.

J Urol. 2026 May;215(5):586. doi: 10.1097/JU.0000000000004938. Epub 2026 Feb 6.

Performance of 99mTc-Sestamibi Single-Photon Emission Computed Tomography/Computed Tomography for Characterizing Renal Masses: Combined Results From a Prospective Scan-and-Resect Trial and Clinical Experience.

Rowe SP, Murtazaliev S, Amindarolzarbi A, Sheikhbahaei S, Meyer AR, Javadi MS, Wood M, Kaufmann B, Goel R, Viglianti BL, Pavlovich CP, Singla N, Pierorazio PM, Baras AS, Epstein JI, Baraban E, Allaf ME, Solnes LB, Oldan JD, Patel HD, Gorin MA.

J Urol. 2026 May;215(5):577-588. doi: 10.1097/JU.0000000000004911. Epub 2025 Dec 23.

Determinants of COVID-19 vaccine hesitancy across 186 countries: a multifaceted analysis using structural equation modeling.

Van Truong L, Van Nguyen T, Trang VTT, Le TTT, Thum CC, Nguyen D, Wong YJ, Jain N, Binh MNLT, Anh DH, Marzouk S, Sabet C, El Idrissi FE, Thuy LT, Huynh KLA, Makram AM, Pham HH, Lesmana E, Simadibrata DM, Abbas AM, Kudsi MA, Minh NA, Ngoc NT, Binh NH, Nam NT, Ali IA, Gurav JS, Tri NHM, Tin PT, Makki A, Albakkar M, Naji MH, Jouini JA, Anand A, Al-Moughales AAAR, Tuyen PB, Kashyap A, Mohamed MHN, Alhosni H, MohamedAhmed BBA, Ramanarayanan S, Menna C, Ramzi A, Arnaout M, James JM, Van Pham M, Mokhtar FMB, Mani E, Kumari U, Fathima SS, Rampengan DDCH, Pham Thi Cam H, Elhadidy AMAM, Okeh DU, Soetomo CT, Latti P, Babu P, Ghanam AK, Osman MOA, Putrinata NPMH, George G, Alhumrani ZAK, Kwaah PA, Saad MA, Ibrahim AID, Mohamed MAS, Dinh XT, Salim J, Bouey J, Huy NT; TMGH Online Research Club Global Team.

Vaccine. 2026 Apr 11;78:128196. doi: 10.1016/j.vaccine.2026.128196. Epub 2026 Mar 17.

Nile red spectroscopy to evaluate disease-specific lipid alterations in glomerular kidney disease.

Swamy A, Teo W, Bau JT, Kline A, Imanzadeh A, Chapman K, Andonegui G, Benediktsson H, Muruve DA, Stys PK, Chun J.

Methods Appl Fluoresc. 2026 Apr 9;14(2). doi: 10.1088/2050-6120/ae56af.

Impact of a factor Xa inhibitor (apixaban) on SIV pathogenesis and response to antiretroviral therapy.

Xu C, Annapureddy H, Carson L, Khurana V, Sivanandham R, Sivanandham S, He T, Raehtz KD, Kim J, Biber C, Arbujas-Silva N, Daira M, Kandasamy S, Feinstein MJ, Sereti I, Apetrei C, Pandrea I.

JCI Insight. 2026 Apr 8;11(7):e202434. doi: 10.1172/jci.insight.202434. eCollection 2026 Apr 8.

Improved progression-free survival following dose-escalated vs. standard dose post-operative radiation therapy for high-risk meningiomas: An International Multicenter Individual Patient Level Meta-Analysis (FIRESTORM).

Singh R, Koempel A, French B, Crawford C, Perlow HK, Rauh S, Kutuk T, Beyer S, Grecula J, Blakaj D, Zhu S, Raval RR, Kotecha R, Chen WC, Raleigh DR, Frechette KM, Lehrer EJ, Khazanchi R, Chaliparambil RK, Sadagopan NS, Ho A, Youngblood MW, Sachdev S, Magill ST, Burgess L, Deng MY, Debus J, König L, Sahgal A, Palmer JD.

Int J Radiat Oncol Biol Phys. 2026 Apr 7:S0360-3016(26)00519-5. doi: 10.1016/j.ijrobp.2026.03.036. Online ahead of print.

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