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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs via the descriptions below.

Affilated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Recent Publications

Region-Specific Decellularization of Porcine Uterine Tube Extracellular Matrix: A New Approach for Reproductive Tissue-Engineering Applications.

Almeida GHDR, da Silva RS, Gibin MS, Gonzaga VHS, Dos Santos H, Igleisa RP, Fernandes LA, Fernandes IC, Nesiyama TNG, Sato F, Baesso ML, Hernandes L, Rinaldi JC, Meirelles FV, Astolfi-Ferreira CS, Ferreira AJP, Carreira ACO.

Biomimetics (Basel). 2024 Jun 24;9(7):382. doi: 10.3390/biomimetics9070382.

The Acari Hypothesis, IV: revisiting the role of hygiene in allergy.

Retzinger AC, Retzinger GS.

Front Allergy. 2024 Jul 10;5:1415124. doi: 10.3389/falgy.2024.1415124. eCollection 2024.

The impact of next-generation sequencing for diagnosis and disease understanding of myeloid malignancies.

Vormittag-Nocito E, Sukhanova M, Godley LA.

Expert Rev Mol Diagn. 2024 Jul 25:1-10. doi: 10.1080/14737159.2024.2383445. Online ahead of print.

BRCA1, BRCA2, and Associated Cancer Risks and Management for Male Patients: A Review.

Cheng HH, Shevach JW, Castro E, Couch FJ, Domchek SM, Eeles RA, Giri VN, Hall MJ, King MC, Lin DW, Loeb S, Morgan TM, Offit K, Pritchard CC, Schaeffer EM, Szymaniak BM, Vassy JL, Katona BW, Maxwell KN.

JAMA Oncol. 2024 Jul 25. doi: 10.1001/jamaoncol.2024.2185. Online ahead of print.

Clear Cell Renal Cell Carcinoma: A Comprehensive Review of its Histopathology, Genetics, and Differential Diagnosis.

Nezami BG, MacLennan GT.

Int J Surg Pathol. 2024 Jul 25:10668969241256111. doi: 10.1177/10668969241256111. Online ahead of print.

Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults.

Litzow MR, Sun Z, Mattison RJ, Paietta EM, Roberts KG, Zhang Y, Racevskis J, Lazarus HM, Rowe JM, Arber DA, Wieduwilt MJ, Liedtke M, Bergeron J, Wood BL, Zhao Y, Wu G, Chang TC, Zhang W, Pratz KW, Dinner SN, Frey N, Gore SD, Bhatnagar B, Atallah EL, Uy GL, Jeyakumar D, Lin TL, Willman CL, DeAngelo DJ, Patel SB, Elliott MA, Advani AS, Tzachanis D, Vachhani P, Bhave RR, Sharon E, Little RF, Erba HP, Stone RM, Luger SM, Mullighan CG, Tallman MS.

N Engl J Med. 2024 Jul 25;391(4):320-333. doi: 10.1056/NEJMoa2312948.

The CCL2-CCR4 axis promotes Regulatory T cell trafficking to canine glioma tissues.

Panek WK, Toedebusch RG, Mclaughlin BE, Dickinson PJ, Van Dyke JE, Woolard KD, Berens ME, Lesniak MS, Sturges BK, Vernau KM, Li C, Miska J, Toedebusch CM.

J Neurooncol. 2024 Jul 24. doi: 10.1007/s11060-024-04766-4. Online ahead of print.

Prediction of differential Gag versus Env responses to a mosaic HIV-1 vaccine regimen by HLA class I alleles.

Nelson GW, van Duijn J, Yuki Y, Pau MG, Tomaka F, Lavreys L, DeRosa SC, McElrath MJ, Kirk GD, Michael NL, Haas DW, Deeks SG, Wolinsky S, Walker B, Barouch DH, Stieh D, Carrington M.

J Virol. 2024 Jul 24:e0028124. doi: 10.1128/jvi.00281-24. Online ahead of print.

Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system.

Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S, Holmes K, Carson M, Shah SJ, Khan S, Clare S, Wunderink RG, Liu H, Walunas T, Cooper L, Yue F, Wehbe F, Fang D, Liebovitz DM, Markl M, Michelson KN, McColley SA, Green M, Starren J, Ackermann RT, D'Aquila RT, Adams J, Lloyd-Jones D, Chisholm RL, Kho A.

Learn Health Syst. 2024 Apr 15;8(3):e10417. doi: 10.1002/lrh2.10417. eCollection 2024 Jul.

Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant.

Gao J, Giro P, Delaney JA, Rasmussen-Torvik L, Taylor KD, Thorp EB, Doyle MF, Feinstein MJ, Sitlani CM, Olson N, Tracy R, Shah SJ, Psaty BM, Patel RB.

ESC Heart Fail. 2024 Jul 22. doi: 10.1002/ehf2.14983. Online ahead of print.

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