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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

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Recent Publications

Verticillium dahliae Elicitor VdSP8 Enhances Disease Resistance Through Increasing Lignin Biosynthesis in Cotton.

Wang Y, Qin J, Wei M, Liao X, Shang W, Chen J, Subbarao KV, Hu X.

Plant Cell Environ. 2025 Jan;48(1):728-745. doi: 10.1111/pce.15170. Epub 2024 Sep 26.

ATEC23 Challenge: Automated prediction of treatment effectiveness in ovarian cancer using histopathological images.

Wang CW, Firdi NP, Chu TC, Faiz MFI, Iqbal MZ, Li Y, Yang B, Mallya M, Bashashati A, Li F, Wang H, Lu M, Xia Y, Chao TK.

Med Image Anal. 2025 Jan;99:103342. doi: 10.1016/j.media.2024.103342. Epub 2024 Sep 5.

Selective synergistic effects of oxalic acid and salicylic acid in enhancing amino acid levels and alleviating lead stress in Zea mays L.

Gupta M, Kumar S, Dwivedi V, Gupta DG, Ali D, Alarifi S, Patel A, Yadav VK.

Plant Signal Behav. 2024 Dec 31;19(1):2400451. doi: 10.1080/15592324.2024.2400451. Epub 2024 Sep 5.

A novel STAT3 CCD inhibitor for suppressing macrophage activation and lipopolysaccharide-induced acute lung injury.

Yang S, Zhou S, Wang W, Cao L, Xue T, Xu J, Lv K, Huang M.

Int Immunopharmacol. 2024 Dec 25;143(Pt 2):113523. doi: 10.1016/j.intimp.2024.113523. Epub 2024 Oct 29.

A Gene Cassette Vd276-280 in Verticillium dahliae Contains Two Genes that Affect Melanized Microsclerotium Formation and Virulence.

Liu T, Yu H, Qin J, Shang W, Chen J, Subbarao KV, Hu X.

Phytopathology. 2024 Dec 6:PHYTO11230426R. doi: 10.1094/PHYTO-11-23-0426-R. Online ahead of print.

In Vivo and Ex Vivo Evaluation of a Novel Method for Topical Delivery of Macromolecules Through the Stratum Corneum for Cosmetic Applications.

Moradi A, Bhatia AC, Behr K, Napekoski K, Foldvari M.

Dermatol Surg. 2024 Dec 5. doi: 10.1097/DSS.0000000000004504. Online ahead of print.

X-chromosome-wide association study for Alzheimer's disease.

Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, van der Lee S, Damotte V, de Rojas I, Palmal S; EADB, GR@ACE, DEGESCO, EADI, GERAD, DemGene, FinnGen, ADGC, CHARGE; Lipton R, Reiman E, McKee A, De Jager P, Bush W, Small S, Levey A, Saykin A, Foroud T, Albert M, Hyman B, Petersen R, Younkin S, Sano M, Wisniewski T, Vassar R, Schneider J, Henderson V, Roberson E, DeCarli C, LaFerla F, Brewer J, Swerdlow R, Van Eldik L, Hamilton-Nelson K, Paulson H, Naj A, Lopez O, Chui H, Crane P, Grabowski T, Kukull W, Asthana S, Craft S, Strittmatter S, Cruchaga C, Leverenz J, Goate A, Kamboh MI, George-Hyslop PS, Valladares O, Kuzma A, Cantwell L, Riemenschneider M, Morris J, Slifer S, Dalmasso C, Castillo A, Küçükali F, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-… See abstract for full author list ➔

Mol Psychiatry. 2024 Dec 4. doi: 10.1038/s41380-024-02838-5. Online ahead of print.

Genetic evidence against involvement of TRPC proteins in SOCE, ROCE, and CRAC channel function.

Susperreguy S, Yamashita M, Choi CI, Liao Y, Burch LH, Blankenship TL, Hayes E, Sliwa T, Zhang Y, Grenet D, Walker M, Plummer NW, Abramowitz J, Kinet JP, Formoso K, Johnson BE, Fleig A, Hazlehurst L, Penner R, Freichel M, Flockerzi V, Prakriya M, Birnbaumer L.

Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2411389121. doi: 10.1073/pnas.2411389121. Epub 2024 Nov 27.

Comparative transcriptomic, epigenomic and immunological analyses identify drivers of disparity in high-grade serous ovarian cancer.

Huang H, Keathley R, Kim U, Cardenas H, Xie P, Wei J, Lengyel E, Nephew KP, Zhao G, Fu Z, Barber EL, Kocherginsky M, Bae-Jump V, Zhang B, Matei D.

NPJ Genom Med. 2024 Dec 2;9(1):64. doi: 10.1038/s41525-024-00448-2.

Sex, cells, and metabolism: Androgens temper Th17-mediated immunity.

Mani NL, Weinberg SE.

J Clin Invest. 2024 Dec 2;134(23):e186520. doi: 10.1172/JCI186520.

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