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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Research Resources

Recent Publications

Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023.

Global Burden of Cardiovascular Diseases and Risks 2023 Collaborators.

J Am Coll Cardiol. 2025 Dec 2;86(22):2167-2243. doi: 10.1016/j.jacc.2025.08.015. Epub 2025 Sep 24.

Surgical Management of Pediatric Primary Hyperoxaluria Type 1: An Eight-Patient Case Series in the Pre-siRNA Era.

Finer G, Darani AN, Switalski MG, Ward SE, Melin-Aldana H, Superina R.

Pediatr Transplant. 2025 Dec;29(8):e70225. doi: 10.1111/petr.70225.

Global, regional, and national sepsis incidence and mortality, 1990-2021: a systematic analysis.

GBD 2021 Global Sepsis Collaborators.

Lancet Glob Health. 2025 Dec;13(12):e2013-e2026. doi: 10.1016/S2214-109X(25)00356-0. Epub 2025 Oct 21.

Quality indicators for cell collections for immune effector cell and gene therapy: recommendations from the American Society for Apheresis.

Aqui NA, Shi PA, Park YA, Tanhehco YC, Thibodeaux SR, Schwartz J, Su L, Gupta GK, Winters JL, Wu YY, Schneiderman J, AlMozain N, Nazli S, Mamo T, Lu W, Lamba DS, Hofmann JC, Liu HD.

Cytotherapy. 2025 Dec;27(12):1457-1462. doi: 10.1016/j.jcyt.2025.08.006. Epub 2025 Aug 29.

Pharmacodynamic insights to support pneumonia treatment in a patient co-infected with two carbapenem-resistant bacteria.

Curry BN, Singh N, Gross AE, Watkins JV, Ozer EA, Karunanidhi A, Sherwood K, Obanor O, Ismail N, Hauser AR, Bulman ZP.

Int J Antimicrob Agents. 2025 Dec;66(6):107633. doi: 10.1016/j.ijantimicag.2025.107633. Epub 2025 Sep 25.

Clinical, Morphologic, and Molecular Findings in MET Fusion Spitz Neoplasms.

Jeyakumar JE, Addo AK, Beydoun HM, Olivares S, Dittmann D, Dos Santos LS, Volek M, Jennings L, Bridges A, Finelt N, Lowe L, Busam KJ, Gerami P.

Am J Dermatopathol. 2025 Dec 1;47(12):930-938. doi: 10.1097/DAD.0000000000003141. Epub 2025 Sep 26.

The global, regional, and national burden attributable to low bone mineral density, 1990-2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021.

GBD 2021 Low Bone Mineral Density Collaborators.

Lancet Rheumatol. 2025 Dec;7(12):e873-e894. doi: 10.1016/S2665-9913(25)00105-5. Epub 2025 Sep 16.

NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomas.

Sadagopan NS, Gomez M, Tripathi S, Billingham LK, DeLay SL, Cady MA, Congivaram HTS, Chia TY, Wan H, Wang S, Raleigh DR, Kaluba FC, Lien EC, Heimberger AB, Lee-Chang C, Youngblood MW, Magill ST, Miska JM.

J Neurooncol. 2025 Dec;175(3):979-991. doi: 10.1007/s11060-025-05208-5. Epub 2025 Sep 9.

A novel technology for margin extension and local control in breast conservation surgery: Saline-coupled intraoperative radiofrequency ablation (SIRA).

Bailey A, Wanke TR, Verma R, Kurth T, Shanley C, Mohr E, Irving S, Klimberg VS, Blanco L, Kulkarni S, Bethke K.

Surg Oncol. 2025 Dec;63:102280. doi: 10.1016/j.suronc.2025.102280. Epub 2025 Sep 1.

Adaptation and changing phenotypes through transgenerational epigenetics.

Van Winkle LJ, Ryznar RJ, Iannaccone PM.

Epigenetics. 2025 Dec;20(1):2460246. doi: 10.1080/15592294.2025.2460246. Epub 2025 Aug 13.

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