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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Access Research Resources

Recent Publications

Life-course socioeconomic position and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Batalha MA, LeCroy MN, Lin J, Peters BA, Qi Q, Wang Z, Wang T, Gallo LC, Talavera GA, McClain AC, Thyagarajan B, Daviglus ML, Hou L, Llabre M, Cai J, Kaplan RC, Isasi CR.

Gut Microbes. 2025 Dec;17(1):2479772. doi: 10.1080/19490976.2025.2479772. Epub 2025 Mar 18.

Efficacy of benznidazole delivery during Chagas disease nanotherapy is dependent on the nanocarrier morphology.

Scariot DB, Staneviciute A, Machado RRB, Yuk SA, Liu YG, Sharma S, Almunif S, Arona Mbaye EH, Nakamura CV, Engman DM, Scott EA.

Biomaterials. 2025 Nov;322:123358. doi: 10.1016/j.biomaterials.2025.123358. Epub 2025 Apr 22.

UTERINE FIBROIDS.

Bulun SE, Yin P, Wei J, Zuberi A, Iizuka T, Suzuki T, Saini P, Goad J, Parker JB, Adli M, Boyer T, Chakravarti D, Rajkovic A.

Physiol Rev. 2025 Oct 1;105(4):1947-1988. doi: 10.1152/physrev.00010.2024. Epub 2025 Apr 11.

Comparison of single-cell long-read and short-read transcriptome sequencing via cDNA molecule matching: quality evaluation of the MAS-ISO-seq approach.

Zajac N, Zhang Q, Bratus-Neuenschwander A, Qi W, Bolck HA, Karakulak T, Oltra TC, Moch H, Kahraman A, Rehrauer H.

NAR Genom Bioinform. 2025 Jul 4;7(3):lqaf089. doi: 10.1093/nargab/lqaf089. eCollection 2025 Sep.

Therapeutic targeting of circTNK2 with nanoparticles restores tamoxifen sensitivity and enhances NK cell-mediated immunity in ER-positive breast cancer.

Wu R, Yu S, Bi A, Li Y, Tiek D, Yu K, Xiong H, Shi Q, Mo Z, Yu X, Song X, Yin F, Wang Y, Yi W, Liu M, Li P, Hu B, Le A, Cheng SY, Zhou B.

Cancer Lett. 2025 Sep 1;627:217823. doi: 10.1016/j.canlet.2025.217823. Epub 2025 May 24.

Pilot phase II study of the combination of lenvatinib (L) and eribulin (E) in advanced solid tumors.

Banwait R, Ko H, Michalek J, Liu Q, Lathrop K, Bowhay-Carnes E, Fotopoulos G, Sarantopoulos J, Elledge R, Taverna J, Karnad A, Siziopikou KP, Kaklamani V.

Int J Cancer. 2025 Aug 15;157(4):752-759. doi: 10.1002/ijc.35446. Epub 2025 Apr 15.

Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis.

Osinga JAJ, Derakhshan A, Karachaliou M, Poppe KG, Warringa L, Verdonk K, Vaidya B, Männistö T, López-Bermejo A, Bassols J, Broeren MAC, Brown SJ, Jensen RC, Popova PV, Pop VJM, Feldt-Rasmussen U, Aminorroaya A, Bliddal S, Mosso L, Chatzi L, Boucai L, Itoh S, Kishi R, Kleynen P, Ashoor G, Oken E, Grineva EN, Lu X, Lertxundi A, Murcia M, Meertens-Gunput STG, Rebagliato M, Riaño-Galán I, Irizar A, Vrijheid M, Fernández-Somoano A, Suvanto E, Guxens M, Daraki V, Mathieu C, Kianpour M, Glintborg D, Jensen TK, Alexander E, Chaker L, Malone F, Messerlian G, Hattersley A, Harley KG, Pearce EN, Visser WE, Vrijkotte TGM, Peeters RP, Palomaki GE, Lowe W, Eskenazi B, Chen LM, Walsh JP, Nicolaides KH, Carty DM, Delles C, Tao FB, Huang K, Maraka S, D'Alton ME, Painter RC, Andersen MS, Benhalima K, Korevaar TIM.

Lancet Diabetes Endocrinol. 2025 Aug;13(8):651-661. doi: 10.1016/S2213-8587(25)00068-3. Epub 2025 Jun 30.

Trends and outcomes for patients receiving neoadjuvant therapy for stage I to III gastric gastrointestinal stromal tumors.

Bennett CF, Janczewski LM, Vitello D, Wells A, Obeidin F, Alexiev BA, Hayes J, Faruqi F, Bentrem D, Wayne JD, Abad J, Hardy A, de Viverios PH, Pollack SM, Chawla A.

J Gastrointest Surg. 2025 Aug;29(8):102117. doi: 10.1016/j.gassur.2025.102117. Epub 2025 Jun 16.

Twist1-induced suppression of oncogene-induced senescence in non-small cell lung cancer requires the transactivation domain of Twist1.

Lafargue A, Wang H, Chettiar ST, Gajula RP, Shetty AC, Song Y, Simons BW, Khan MA, Nguyen T, Tseng HW, Chang J, Waters DN, Chan A, Lam C, Carrieri FA, Smack C, Connis N, Chowdhury DD, Nugent K, Siddiqui I, Taparra K, Rezaee M, Zachara N, Morris ZS, McFarland C, Abdulkadir SA, Hann CL, Tran PT.

Neoplasia. 2025 Aug;66:101179. doi: 10.1016/j.neo.2025.101179. Epub 2025 May 22.

Unlocking the Radiosensitizing Potential of MYC Inhibition in Neuroendocrine Malignancies.

Guo Q, Yang W, Robinson G, Chaludiya K, Abdulkadir AN, Roy FG, Shivakumar D, Ahmad AN, Abdulkadir SA, Kirschner AN.

Int J Radiat Oncol Biol Phys. 2025 Aug 1;122(5):1310-1326. doi: 10.1016/j.ijrobp.2025.04.034. Epub 2025 May 10.

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