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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

Read Full Message

Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs.

Research Areas

Affiliated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Research Resources

Recent Publications

NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomas.

Sadagopan NS, Gomez M, Tripathi S, Billingham LK, DeLay SL, Cady MA, Congivaram HTS, Chia TY, Wan H, Wang S, Raleigh DR, Kaluba FC, Lien EC, Heimberger AB, Lee-Chang C, Youngblood MW, Magill ST, Miska JM.

J Neurooncol. 2025 Dec;175(3):979-991. doi: 10.1007/s11060-025-05208-5. Epub 2025 Sep 9.

Adaptation and changing phenotypes through transgenerational epigenetics.

Van Winkle LJ, Ryznar RJ, Iannaccone PM.

Epigenetics. 2025 Dec;20(1):2460246. doi: 10.1080/15592294.2025.2460246. Epub 2025 Aug 13.

Life-course socioeconomic position and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Batalha MA, LeCroy MN, Lin J, Peters BA, Qi Q, Wang Z, Wang T, Gallo LC, Talavera GA, McClain AC, Thyagarajan B, Daviglus ML, Hou L, Llabre M, Cai J, Kaplan RC, Isasi CR.

Gut Microbes. 2025 Dec;17(1):2479772. doi: 10.1080/19490976.2025.2479772. Epub 2025 Mar 18.

Shelter in place: live CLL cells inside the bone marrow fibroblasts and its implication in residual disease persistence.

Lu P, Franzen CA, Vistarop A, Efimov A, Shahriyar SA, Wang S, Rao S, Messmer M, Nakhoda S, Cukierman E, Ma S, Franco-Barraza J, Gao J, Wang YL.

Blood Neoplasia. 2025 Jul 25;2(4):100142. doi: 10.1016/j.bneo.2025.100142. eCollection 2025 Nov.

Posttranscriptional activity of eIF4E contributes to HoxA9-driven leukemogenesis.

Zhou F, Culjkovic-Kraljacic B, Bach C, Feng L, Mishima Y, Borden KLB, Tenen DG.

Blood Neoplasia. 2025 Jun 30;2(4):100132. doi: 10.1016/j.bneo.2025.100132. eCollection 2025 Nov.

Injury to repair: Functions of microglia and monocyte-derived cells in ischemic stroke.

Martynowicz R, Sullivan DP, Batra A.

J Stroke Cerebrovasc Dis. 2025 Nov;34(11):108422. doi: 10.1016/j.jstrokecerebrovasdis.2025.108422. Epub 2025 Sep 17.

Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML.

Lin AY, Rink JS, Yang E, Small S, Gerber JJ, Zak TJ, Altman J, Abaza Y, Platanias LC, Gordon LI, Thaxton CS.

Blood Neoplasia. 2025 Jun 3;2(4):100122. doi: 10.1016/j.bneo.2025.100122. eCollection 2025 Nov.

Risk assessment and underlying mechanisms of pydiflumetofen resistance in Alternaria tenuissima and Alternaria alternata.

Luo L, Shao G, Li X, Dai T, Miao J, Lu X, Peng Q, Liu X.

Pestic Biochem Physiol. 2025 Nov;214:106584. doi: 10.1016/j.pestbp.2025.106584. Epub 2025 Jul 19.

Corrigendum to Evidence and Consensus-Based Imaging Guidelines in Multifocal Choroiditis With Panuveitis and Punctate Inner Choroiditis-Multimodal Imaging in Uveitis (MUV) Taskforce Report 5. Am J Ophthalmol. 2025;276:272-285.

Gangaputra S, Agarwal A, Norel JO, Tsui E, Thorne JE, de-la-Torre A, Altaweel M, Biswas J, Sadda S, Invernizzi A, Agrawal R, Shantha JG, Accorinti M, Fawzi A, Jabs DA, Sarraf D, Gupta V; Collaborators: Multimodal Imaging in Uveitis (MUV) Task force.

Am J Ophthalmol. 2025 Nov;279:588-590. doi: 10.1016/j.ajo.2025.08.027. Epub 2025 Aug 29.

Piperacillin/tazobactam clearance predicted by non-creatinine based estimates of GFR in critically ill adults.

Barreto EF, Chang J, Rule AD, Cole KC, Fogelson L, Paul J, Jannetto PJ, Athreya AP, Scheetz MH; BLOOM Study Group.

Int J Antimicrob Agents. 2025 Nov;66(5):107586. doi: 10.1016/j.ijantimicag.2025.107586. Epub 2025 Aug 7.

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